Resources

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Trend and Outcome of Notified Children with Tuberculosis during 2011-2015 in Kampala, Uganda [1]

This was a retrospective study of TB data for Kampala City for the period 2011–2015. We extracted data from the TB registers in the 52 diagnostic and treatment units in Kampala. We report on data for children 0 to 14 years. We accessed 33,221 TB patient records, of which 2,333 (7%) were children. The proportion of children with pulmonary TB was 80%. The TB notification rate among children in Kampala City showed a large decline (from 105 to 74 per 100,000) during the period. There was a slight improvement in the treatment success rate among the children.

High Levels of Dual-Class Drug Resistance in HIV-Infected Children Failing First-Line Antiretroviral Therapy in Southern Ethiopia [2]

Clinical monitoring of pediatric HIV treatment remains a major challenge in settings where drug resistance genotyping is not routinely available. As a result, our understanding of drug resistance, and its impact on subsequent therapeutic regimens available in these settings, remains limited. We investigate the prevalence and correlates of HIV-1 drug resistance among 94 participants of the Ethiopia Pediatric HIV Cohort failing first-line combination antiretroviral therapy (cART) using dried blood spot-based genotyping. Overall, 81% (73/90) of successfully genotyped participants harbored resistance mutations. Strikingly, 42% of resistant participants harbored resistance to all four nucleoside reverse transcriptase inhibitors recommended for second-line use in this setting, meaning that there are effectively no remaining cART options for these children. Longer cART duration and prior regimen changes were significantly associated with detection of drug resistance mutations. Replicate genotyping increased the breadth of drug resistance detected in 34% of cases, and thus is recommended for consideration when typing from blood spots. Implementation of timely drug resistance testing and access to newer antiretrovirals and drug classes are urgently needed to guide clinical decision-making and improve outcomes for HIV-infected children on first-line cART in Ethiopia.

Factors Promoting and Inhibiting Sustained Impact of a Mental Health Task-shifting Program for HIV Providers in Ethiopia [3]

Task-shifting mental health into general medical care requires more than brief provider training. Generalists need long-term support to master new skills and changes to work context are required to sustain change in the face of competing priorities. We examined program and context factors promoting and obstructing sustainability of a mental health task-shifting training for hospital-based HIV providers in Ethiopia.

Community Interventions to Improve Access to TB Services in Afghanistan [4]

Afghanistan has made remarkable improvements in health indicators since 2005. However, a wide range of barriers prevent rural communities in Afghanistan from accessing tuberculosis (TB) and other health services.

Lea Mimba Project Overview [6]

In 2017, with funding by UK Aid from the British people, Management Sciences for Health (MSH) launched the Lea Mimba project to address gaps in the quality of antenatal care (ANC) and to support women's and adolescents' use of maternal and newborn health services in Kakamega County, Kenya.

Toward Building Resilient Pharmaceutical Systems [8]

SIAPS Final Report

SPS Afghanistan Associate Award Final Report [10]

In 2008, the USAID Mission invited the Strengthening Pharmaceutical Systems (SPS) Program to provide technical assistance and support to the Government of Afghanistan’s Ministry of Public Health (MoPH) to improve the pharmaceutical system.

Electronic Infectious Disease Surveillance and Response (eIDSR) System in Rwanda [12]

Outbreaks can overwhelm weak or fragile health systems that lack the tools, infrastructure, policies, and systems to keep communities healthy and safe. Timely detection, preparedness, and appropriate response are essential for limiting both the loss of human life and crippling political and socio-economic impact of disease outbreaks.

On the Road to UHC: Leave No One Behind [14]

[15]

A civil society organisation (CSO) perspective on how UHC can be reached by 2030 Universal Health Coverage 2030 (UHC2030) MSH is the secretariat for the Civil Society Engagement Mechanism of UHC2030, a global movement to build stronger health systems for universal health coverage.

Comparison of the Yield of Tuberculosis among Contacts of Multidrug-resistant and Drug-sensitive Tuberculosis Patients in Ethiopia Using GeneXpert as a Primary Diagnostic Test [16]

This study compared the yield of TB among contacts of multidrug-resistant tuberculosis (MDR-TB) index cases with that of drug-sensitive TB (DS-TB) index cases in a program setting. The yield of TB among contacts of MDR-TB and DS-TB using GeneXpert was high as compared to population-level prevalence. The likelihood of diagnosing RR (Rifampicin Resistant)-TB among contacts of MDR-TB index cases is higher in comparison with contacts of DS-TB index cases. The use of GeneXpert in DS TB contact investigation has an added advantage of diagnosing RR cases in contrast to using the nationally recommended AFB microscopy for DS TB contact investigation.

Awareness and Perceptions of Emergency Contraceptive Pills among Women in Kinshasa, Democratic Republic of the Congo [17]

Despite the commitment of the Democratic Republic of the Congo (DRC) to expand the family planning method mix and increase access to services, awareness of emergency contraception is low among women, and the method remains underused and poorly integrated in family planning programming. Data from 15 focus group discussions conducted in 2016 among women aged 15–35 were used to examine awareness and perceptions of, and attitudes toward, emergency contraceptives. Emergency contraceptive pills have the potential to address gaps in the family planning method mix in the DRC. Assessing whether women have incomplete or erroneous information about family planning methods can provide better understanding of women's contraceptive choices in low-income countries.

Estimating Road Traffic Injuries in Jinja District, Uganda, Using the Capture-recapture Method [18]

Road traffic injuries (RTIs) are commonly under-reported in low- and-medium-income countries. This study aimed to estimate the number of RTIs and determine the magnitude of under-reporting by traffic police and hospital registries. The police registry captured 14.4% of the estimated number of RTIs and the hospitals captured 60.4%. The estimated number of RTIs was higher than reported by either the police or the hospitals alone. Neither the police nor the hospitals provided accurate data on RTIs, calling for the strengthening of both sources of data.

Multidisciplinary and Multisectoral Coalitions as Catalysts for Action against Antimicrobial Resistance: Implementation Experiences at National and Regional Levels [19]

Building coalitions can amplify stakeholder efforts to carry out effective AMR prevention and control strategies. We have developed and implemented an approach to help local stakeholders kick-start the coalition-building process. The five-step process is to (1) mobilise support, (2) understand the local situation, (3) develop an action plan, (4) implement the plan, and (5) monitor and evaluate. Our experience with the coalition-building approach in Ethiopia, Namibia, Zambia, and with the Ecumenical Pharmaceutical Network shows that coalitions can form in a variety of ways with many different stakeholders, including government, academia, and faith-based organisations, to organise actions to preserve the effectiveness of existing antimicrobials and contain AMR.

Prevention of Mother-to-Child Transmission of HIV: A Cross-sectional Study in Malawi [20]

We conducted a cross-sectional analysis of 33,744 mother–infant pairs to estimate the use and outcomes of the Malawian programme for the prevention of mother-to-child transmission (MTCT) of human immunodeficiency virus (HIV). Most women used the Malawian programme for the prevention of MTCT. The risk of MTCT increased if any of the four main steps in the programme were missed.

RFP for Diagnostic Connectivity, Afghanistan [21]

Challenge TB (CTB) is a global USAID-funded project, working in Afghanistan. CTB/Afghanistan is a five year project effective from January 2015-September 2019. Globally, it is implemented in partnership with MSH, KNCV, WHO, Ministry of Public Health (MoPH)/National Tuberculosis Program (NTP), WHO, JICA, Global Fund and locally, by BPHS implementers.

Community Approaches Successful in Preventing, Treating Malaria [22]

Technical Highlight Malaria is responsible for about 7% of all deaths in children under five in Madagascar. The USAID Mikolo Project promoted community approaches to prevent and treat malaria by working with health facilities, community health volunteers (CHVs), and families.

Strengthening the Vertical Continuum of Care [24]

Technical Highlight

Empowering Women with Access to Savings, Credit, and Health Messages [26]

Technical Highlight

Improving the Quality of Community-Based Care [28]

Technical Highlight

Improving Health Care Service Delivery and Data Quality through mHealth [30]

Technical Highlight

Expanding the Life Cycle Continuum of Care [32]

Technical Highlight

Five Years of Health Impact, 10 Stories of Success [34]

We are pleased to share this booklet that summarizes 10 of the best stories we’ve collected from the field. These narratives are a legacy to Madagascar’s health system and for future public health interventions in the country.

Harmonizing National Abortion and Pregnancy Prevention Laws and Policies for Sexual Violence Survivors with the Maputo Protocol: Proceedings of a 2016 Regional Technical Meeting in Sub-Saharan Africa [36]

In April 2016, the Population Council, in partnership with the World Health Organization (WHO) and the International Consortium for Emergency Contraception, convened a regional meeting in Lusaka, Zambia, geared toward supporting countries in East and Southern Africa in meeting their obligations under the Maputo Protocol. Government and civil society representatives from six countries participated: Botswana, Ethiopia, Kenya, Malawi, Rwanda, and Zambia. The meeting was the first activity in a joint project of technical assistance by the conveners, aimed at strengthening access to comprehensive post-rape care for survivors of sexual violence. The regional technical meeting concluded with a discussion of practical steps that participants could take to facilitate legal, policy, and program reform with respect to pregnancy prevention and safe abortion in their respective countries.

MSH Nigeria Newsletter: December 2017 [37]

In this edition, you will read about MSH support to Society for Women and Children Living with HIV/AIDS in Nigeria (SOWCHAN) advocacy march to the National Assembly on World Aids Day; how we are applying gender lens in Nigeria; and mitigating human resource gaps in general hospital Minna.

MSH Nigeria Newsletter: April 2018 [39]

In this edition, you will read about MSH’s work in ensuring that Or- phans and Vulnerable Children (OVC) return to school in Nigeria, HIV Polymerase Chain Reaction (PCR) laboratory transitioned to the Global Fund and FHI360.

Pages

Links
[1] https://www.msh.org/resources/trend-and-outcome-of-notified-children-with-tuberculosis-during-2011-2015-in-kampala?p=43&page=35
[2] https://www.msh.org/resources/high-levels-of-dual-class-drug-resistance-in-hiv-infected-children-failing-first-line?p=43&page=35
[3] https://www.msh.org/resources/factors-promoting-and-inhibiting-sustained-impact-of-a-mental-health-task-shifting-program?p=43&page=35
[4] https://www.msh.org/resources/community-interventions-to-improve-access-to-tb-services-in-afghanistan?p=43&page=35
[5] https://www.msh.org/resources/community-interventions-to-improve-access-to-tb-services-in-afghanistan
[6] https://www.msh.org/resources/lea-mimba-project-overview?p=43&page=35
[7] https://www.msh.org/resources/lea-mimba-project-overview
[8] https://www.msh.org/resources/toward-building-resilient-pharmaceutical-systems?p=43&page=35
[9] https://www.msh.org/resources/toward-building-resilient-pharmaceutical-systems
[10] https://www.msh.org/resources/sps-afghanistan-associate-award-final-report?p=43&page=35
[11] https://www.msh.org/resources/sps-afghanistan-associate-award-final-report
[12] https://www.msh.org/resources/electronic-infectious-disease-surveillance-and-response-eidsr-system-in-rwanda?p=43&page=35
[13] https://www.msh.org/resources/electronic-infectious-disease-surveillance-and-response-eidsr-system-in-rwanda
[14] https://www.msh.org/resources/on-the-road-to-uhc-leave-no-one-behind?p=43&page=35
[15] https://www.msh.org/resources/on-the-road-to-uhc-leave-no-one-behind
[16] https://www.msh.org/resources/comparison-of-the-yield-of-tuberculosis-among-contacts-of-multidrug-resistant-and-drug?p=43&page=35
[17] https://www.msh.org/resources/awareness-and-perceptions-of-emergency-contraceptive-pills-among-women-in-kinshasa?p=43&page=35
[18] https://www.msh.org/resources/estimating-road-traffic-injuries-in-jinja-district-uganda-using-the-capture-recapture?p=43&page=35
[19] https://www.msh.org/resources/multidisciplinary-and-multisectoral-coalitions-as-catalysts-for-action-against?p=43&page=35
[20] https://www.msh.org/resources/prevention-of-mother-to-child-transmission-of-hiv-a-cross-sectional-study-in-malawi?p=43&page=35
[21] https://www.msh.org/resources/rfp-for-diagnostic-connectivity-afghanistan?p=43&page=35
[22] https://www.msh.org/resources/community-approaches-successful-in-preventing-treating-malaria?p=43&page=35
[23] https://www.msh.org/resources/community-approaches-successful-in-preventing-treating-malaria
[24] https://www.msh.org/resources/strengthening-the-vertical-continuum-of-care?p=43&page=35
[25] https://www.msh.org/resources/strengthening-the-vertical-continuum-of-care
[26] https://www.msh.org/resources/empowering-women-with-access-to-savings-credit-and-health-messages?p=43&page=35
[27] https://www.msh.org/resources/empowering-women-with-access-to-savings-credit-and-health-messages
[28] https://www.msh.org/resources/improving-the-quality-of-community-based-care?p=43&page=35
[29] https://www.msh.org/resources/improving-the-quality-of-community-based-care
[30] https://www.msh.org/resources/improving-health-care-service-delivery-and-data-quality-through-mhealth?p=43&page=35
[31] https://www.msh.org/resources/improving-health-care-service-delivery-and-data-quality-through-mhealth
[32] https://www.msh.org/resources/expanding-the-life-cycle-continuum-of-care?p=43&page=35
[33] https://www.msh.org/resources/expanding-the-life-cycle-continuum-of-care
[34] https://www.msh.org/resources/five-years-of-health-impact-10-stories-of-success?p=43&page=35
[35] https://www.msh.org/resources/five-years-of-health-impact-10-stories-of-success
[36] https://www.msh.org/resources/harmonizing-national-abortion-and-pregnancy-prevention-laws-and-policies-for-sexual?p=43&page=35
[37] https://www.msh.org/resources/msh-nigeria-newsletter-december-2017?p=43&page=35
[38] https://www.msh.org/resources/msh-nigeria-newsletter-december-2017
[39] https://www.msh.org/resources/msh-nigeria-newsletter-april-2018?p=43&page=35
[40] https://www.msh.org/resources/msh-nigeria-newsletter-april-2018
[41] https://www.msh.org/resources/request-for-proposal-no-safemed-2018-04?p=43
[42] https://www.msh.org/resources/request-for-proposal-no-safemed-2018-04?p=43&page=34
[43] https://www.msh.org/resources/request-for-proposal-no-safemed-2018-04?p=43&page=31
[44] https://www.msh.org/resources/request-for-proposal-no-safemed-2018-04?p=43&page=32
[45] https://www.msh.org/resources/request-for-proposal-no-safemed-2018-04?p=43&page=33
[46] https://www.msh.org/resources/request-for-proposal-no-safemed-2018-04?p=43&page=36
[47] https://www.msh.org/resources/request-for-proposal-no-safemed-2018-04?p=43&page=37
[48] https://www.msh.org/resources/request-for-proposal-no-safemed-2018-04?p=43&page=38
[49] https://www.msh.org/resources/request-for-proposal-no-safemed-2018-04?p=43&page=39
[50] https://www.msh.org/resources/request-for-proposal-no-safemed-2018-04?p=43&page=57